Genetic link between breast condition and invasive breast cancer uncovered

Anne Li                                                                                     January 20th, 2018


The genetics behind how a breast condition becomes invasive breast cancer may be explained by a new study. Gene changes in invasive breast cancer cells were also found in abnormal cell growths called ductal carcinoma in situ (DCIS), a potentially pre-cancerous breast condition, according to the study published in Cell. The findings suggest that these genetic faults may play a role in transforming these abnormal cells into invasive breast cancer cells. Dr Jelle Wesseling, who is leading similar work funded by Cancer Research UK and the Dutch Cancer Society to understand which women with DCIS will develop breast cancer, said the research is an important step to learn how DCIS can develop in to invasive breast cancer. Such progression occurs in up to 3 in 10 cases of DCIS, according to the researchers.


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