Targeting cancer spread: keeping breast tumours under LOX and key

Anne Li                                                                                               April 23rd, 2017


Tumours that have spread around the body are trickier to treat successfully. So finding molecules that help cancers progress, and developing ways to disable them, is crucial in tackling advanced tumours. LOX is one such molecule. Short for ‘lysyl oxidase,’ its main job is to help form a supportive scaffold around cells called the extracellular matrix, which gives tissues their structure. That’s a hugely important role in the body. But LOX also has a dark side. Research has suggested it can rejig the extracellular matrix in such a way that not only encourages tumours to grow, but also helps them spread.


See original article at: http://scienceblog.cancerresearchuk.org/2017/04/18/targeting-cancer-spread-keeping-tumours-under-lox-and-key/

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