Genetic predisposition to breast cancer due to non-BRCA mutations in Ashkenazi Jewish women

Anne LI                           7/22/2017                          anne2001.li@gmail.com


Genetic mutations in BRCA1 and BRCA2 increase the risk of breast and ovarian cancer in Ashkenazi Jewish women. A new article published by JAMA Oncology examines the likelihood of carrying another cancer-predisposing mutation in BRCA1, BRCA2 or another breast cancer gene among women of Ashkenazi Jewish ancestry with breast cancer who do not carry one of the founder mutations. Mary-Claire King, Ph.D., of the University of Washington, Seattle, and coauthors sequenced genomic DNA of 1,007 women of Ashkenazi Jewish ancestry with breast cancer for known and candidate breast cancer genes.


See original article at: https://www.sciencedaily.com/releases/2017/07/170720142306.htm



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