Checkpoint inhibitors fire up different types of T cells to attack tumors

Anne Li                                                                                     August 12th, 2017                                    anne2001.li@gmail.com


Cancer immunotherapies that block two different checkpoints on T cells launch immune attacks on cancer by expanding distinct types of T cell that infiltrate tumors. Researchers analyzed infiltrating immune cells from mouse tumor models and human melanomas treated with either anti-CTLA-4 or anti PD-1 checkpoint inhibitors. Using mass cytometry, they analyzed 33 surface markers and 10 intracellular markers to characterize infiltrating cells.


See original article at: https://www.sciencedaily.com/releases/2017/08/170810124952.htm

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