Researchers “drug the undruggable” through unique collaboration

Anne Li                                                                                      October 28th, 2017


A new approach to targeting key cancer-linked proteins, thought to be ‘undruggable’, has been discovered through an alliance between industry and academia created by Cancer Research UK. The results of the study, published in Nature(link is external)*, show that two novel and specific small-molecule inhibitors developed by the alliance can bind to and deactivate an enzyme that controls the stability of the p53 tumour suppressor protein. This deactivation allows p53 to be turned on, putting the brakes on cancer growth.


See original article at: https://www.cancerresearchuk.org/about-us/cancer-news/press-release/2017-10-18-researchers-drug-the-undruggable-through-unique-collaboration

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