Global Cancer News

Synthetic biologists extend functional life of cancer fighting circuitry in microbes

Bioengineers at the University of California San Diego have developed a method to significantly extend the life of gene circuits used to instruct microbes to do things such as produce and deliver drugs, break down chemicals and serve as environmental sensors. Most of the circuits that synthetic biologists insert into microbes break or vanish entirely from the microbes after a certain period of time — typically days to weeks — because of various mutations. But in the September 6, 2019 issue of the journal Science, the UC San Diego researchers demonstrated that they can keep genetic circuits going for much longer.


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