Source: Cancer Quest Overview of Metastases The majority of deaths (about 90%) associated with cancer are due to the metastasis of the original tumor cells to sites distant from the initial or primary tumor. Metastasis is the process by which cancer cells migrate throughout the body. In order for cells to move through…...
Sponge on a string test to transform oesophageal cancer diagnosis
Barrett’s oesophagus is a condition that can lead to oesophageal cancer in a small number of people. It’s usually diagnosed in hospital by endoscopy (passing a camera down into the stomach) following a GP referral for longstanding heartburn symptoms. The Cytosponge test, developed by researchers at the University of Cambridge, is…...
Protection from UV Rays
AFCR encourages everyone to wear sunglasses, sunscreen, and wide-brimmed hats whenever spending prolonged time outdoors. Be prepared! If you are planning to spend time outside, pay attention to the day’s UV Index and take appropriate precautions. • Make sure your sunglasses block 99 to 100 percent of both types of…...
Breakthrough discovery to transform prostate cancer treatment
A novel formulation of the prostate cancer drug abiraterone acetate — currently marketed as Zytiga — will dramatically improve the quality of life for people suffering from prostate cancer, as pre-clinical trials by the University of South Australia show the new formulation improves the drug’s effectiveness by 40 per cent.…...
Popular chemotherapy drug may be less effective in overweight and obese women
Breast cancer patients who are overweight or obese might benefit less from treatment with docetaxel, a common chemotherapy drug, than lean patients. An international team of researchers based this conclusion on a retrospective analysis of data from a large clinical trial. In most European countries, more than 50% of women…...
How cancer drugs find their targets could lead to a new toolset for drug development
In the watery inside of a cell, complex processes take place in tiny functional compartments called organelles. These compartments are bound by thin membranes. But in the past few years, research at Whitehead Institute and elsewhere has shown that there are other cellular organelles held together without a membrane. These…...
AACR Virtual Annual Meeting I presents new data on cancer biology, treatment, screening, risk reduction
Brief points covered in the America Association for Cancer Research (AACR) Virtual Annual Meeting I held on April 27-28th: -Treating BRAF-Positive Melanoma by adding checkpoint inhibitor Tecentriq (atezolizumab) to a combination of two targeted drugs Zelboraf (vemurafenib) and Cotellic (cobimetinib) -PARP Inhibitor (targeted drugs that inhibit DNA damage repair) are…...
Link between Children with Cancer and COVID-19
May 16th, 2020 A study indicates that children with cancer are not at increased risks of severe cases of COVID-19, and researchers find that Medicaid expansion was associated with reduced cancer deaths. Read more at: https://www.cancertodaymag.org/Pages/cancer-talk/May-15-The-Week-in-Cancer-News.aspx...
FDA Approves Pemazyre (Pemigatinib) for Bile Duct Cancer
The US Food and Drug Administration (FDA) approved the first targeted therapy for bile duct cancer. Pemazyre (pemigatinib) is for adults with advanced bile duct cancer whose cancer has grown after at least one previous chemotherapy treatment and whose tumors have a mutation in the FGFR2 gene. Full information at: https://www.cancer.org/latest-news/fda-approves-pemazyre-pemigatinib-for-bile-duct-cancer.html...
FDA Approves Trodelvy (Sacituzumab govitecan-hziy) for Triple Negative Breast Cancer
The US Food and Drug Administration (FDA) approved a new type of therapy for triple-negative breast cancer that has spread to other parts of the body and hasn’t responded to other treatments. Triple-negative breast cancer is called that because the cancer cells don’t have estrogen or progesterone receptors and also…...