Using a non-invasive imaging technique that measures the stiffness of tissues gives crucial new information about cancer architecture and could aid the delivery of treatment to the most challenging tumours, new research shows. Magnetic resonance elastography was able to visualise and measure how stiff and dense tumours are in mice.…...
Quest for new cancer treatment crosses milestone
A cancer therapy invented at Rice University has crossed a milestone in clinical trials, a major development in a decades long quest to develop a treatment that destroys tumors without the debilitating side effects of chemotherapy, invasive surgery and radiation. According to the study, thirteen of the first 15 prostate cancer…...
Tasmanian devil research could help tackle immunotherapy resistance
A cluster of interacting proteins that are active in both human cancers and Tasmanian devil facial tumours, may give clues to how cancers evade the immune system. This early work in cells could one day guide us towards new drug combinations that improve the effectiveness of immunotherapy treatments. Researchers at…...
Scientists evaluate cancer risk of US drinking water
Researchers from the Environmental Working Group (EWG) in Washington, DC, used a new approach to analyze cumulative cancer risk due to carcinogens in tap water across the U.S. This study is the first to apply a “cumulative cancer risk framework” to the analysis of tap water contaminants for the whole of the U.S.…...
Breakthrough in understanding enzymes that make antibiotic for drug-resistant pathogen
Acinetobacter baumannii is a pathogen that causes hospital-acquired infections that are very difficult to treat, because they are resistant to most currently available antibiotics. As one of the World Health Organization’s three critical priority pathogens, new antibiotics for Acinetobacter baumannii are urgently needed, and is now one step closer to being tackled, as…...
Disparities in toxic heavy metal exposures correlated with increased risk of breast cancer among minority populations
Among women in Chicago, African Americans and Hispanics were exposed to higher levels of ambient toxic heavy metals compared with non-Hispanic whites, and this increased exposure correlated with increased incidence of breast cancer. Garth Rauscher, Ph.D., associate professor of epidemiology at the University of Illinois at Chicago School of Public…...
Discovery of how colorectal cancer drug works will help more patients
Some colorectal cancer patients with a certain gene mutation benefit from a chemotherapy drug called cetuximab, although the mechanism of how this drug worked was unknown. Scientists have combined computational biology with experimental investigations to discover, for the first time, the mechanism for why these patients respond to the drug,…...
4 gold molecules point to the future of cancer treatment
For the past few decades, platinum based cisplatin has been a compound of choice in the treatment of many cancers. It is especially effective at halting testicular cancer, with a success rate of more than 90%. However, the usefulness of cisplatin and other metal based cancer drugs has been limited due to…...
Prostate Cancer Risk Spikes In Men With IBD
A recent study has found that men with inflammatory bowel disease may be up to five times more likely to have prostate cancer than those without the condition, and when they have it, the cancer is more aggressive. The findings, from a single-center analysis that included more than 10,000 patients,…...
Breast cancer metastasis: Immune cells called PoEMs promote spread of cancer cells
When breast cancer cells spread through the body, they do so mainly through the lymph system that normally removes excess fluid and waste products from our tissues. Now, scientists from the group of Professor Massimiliano Mazzone (VIB-KU Leuven Center for Cancer Biology) identified a novel subset of immune cells, called…...