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Olfactory receptors: New molecular targets detected in colorectal cancer cells

Anne Li                                                                                                March 25th, 2017

 

Growth of colorectal cancer cells can be inhibited with the odorant troenan. This is reported by the research team headed by Prof Dr Dr Dr habil. Hanns Hatt and Dr Lea Weber from Ruhr-Universität Bochum in the journal PLOS ONE. The researchers detected the olfactory receptor OR51B4 in tumour cells taken from the rectum and colon cancer cell lines. They analysed which odorant activates the receptor and in what way the activation affects the cells. For the purpose of the study, the team from the Department for Cellphysiology in Bochum collaborated with the Department of Molecular GI-Oncology at Ruhr-Universität, headed by Prof Dr Stephan Hahn. The necessary gene sequencing was carried out by the team from the Cologne Center for Genomics.

 

See original article at: https://www.sciencedaily.com/releases/2017/03/170323141329.htm

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