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Scientists ID human protein essential for human cytomegalovirus replication

Anne Li                                                                                                May 13th, 2017

 

HCMV infects 30 to 100 percent of people worldwide, depending on socioeconomic status. While most remain symptom-free, HCMV can be dangerous or deadly for people with weakened immune systems or for babies infected before birth. Some HCMV treatments exist, but their benefits are limited, and scientists are investigating new ways to treat and prevent infection. To better understand how HCMV replicates during active infection, Yao-Tang Lin and colleagues at the University of Edinburgh, U.K., performed a search for human genes needed by the virus for replication. They found that reducing the expression of the VCP gene in HCMV-infected human cells significantly reduced viral replication in the cells.

 

See original article at: https://www.sciencedaily.com/releases/2017/05/170511165353.htm

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