Scientists exploit leaks in blood brain barrier to treat glioblastoma

Anne Li                                                                                     November 10th, 2017


An ovarian cancer drug can leak through the blood brain barrier to reach brain tumours and could be an effective treatment for glioblastoma, suggest results presented at the National Cancer Research Institute’s (NCRI) Cancer Conference in Liverpool. The Cancer Research UK-funded OPARATIC trial, which was managed by the charity’s Centre for Drug Development, tested whether the ovarian cancer drug olaparib could reach glioblastoma, a type of brain tumour which is very difficult to treat. And early results show it successfully reaches brain tumours at high enough levels for treatment. The successful delivery of this drug is an important step as many others have failed to reach the tumour.


See original article at: https://www.cancerresearchuk.org/about-us/cancer-news/press-release/2017-11-06-scientists-exploit-leaks-in-blood-brain-barrier-to-treat-glioblastoma

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