To understand what has gone wrong when cancer occurs and to create new possibilities for treatment, it is important to understand the molecular mechanisms behind what is happening at the cellular level. New research, which is now published in the journal Molecular Cell, explains how the motor of an enzyme in DNA damage repair is switched on and off and how these processes might go awry in cancer. Our genetic information is packaged into highly compact structures called chromatin. The way in which chromatin is packaged regulates many vital processes that require access to the cell’s genetic material. ATP-dependent chromatin remodelers are enzymes specialised in altering the structure and packaging of chromatin.
See original article at: https://www.sciencedaily.com/releases/2017/12/171207140917.htm