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Artificial sweetener could someday provide cancer treatments with fewer side effects

Anne Li                                                                                     January 26th, 2018

 

Artificial sweeteners are used in diet drinks and foods but also could someday be used as treatments targeting carbonic anhydrase IX (CA IX), a protein associated with aggressive cancers. Although several drugs have been approved that target similar forms of CA, they aren't selective and may cause side effects, including vomiting and fatigue. Now researchers report that an artificial sweetener could lead to development of a more selective therapy.  CA IX is a zinc protein that is typically found only in the gastrointestinal tract, but it is overexpressed in cancer tissues and contributes to the growth and spread of malignant cells in lung, brain and breast cancers.
 
See original article at: https://www.sciencedaily.com/releases/2018/01/180124114153.htm

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