Innovative Therapies and Treatments
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Building Safer, More Effective CAR-T Cell Therapies for Cancer Patients
August 16, 2022 Innovative Therapies and Treatments, Translational Research
CAR-T Cell Therapies are Not Working Against Solid Cancers
Doctors divide cancer into two main types: solid tumor cancers and cancers in the blood. Solid cancer is an abnormal mass of tissue in a ‘solid’ organ such as the breast or prostate.…
Revolutionary Drug Delivery Platform: Improves Effectiveness and Tolerability of Cancer Treatments
November 15, 2021 Innovative Therapies and Treatments, Translational Research
THE CHALLENGE ——Patient Circumstances Limit Potential Viable Therapies
Patients afflicted with tumors and cancers are in need of urgent, active intervention in order to have the best possibilities for treatment success and a favorable outcome. The majority of such patients often present…
Changing the Oncology Treatment Paradigm For Oral Cancers
September 13, 2021 AFCR News, Clinical Research, Innovative Therapies and Treatments
THE CHALLENGE ——Oral Cancer Survival Rate Has Only Improved 5% in the Last Decade and Patients Can Have a Severely Compromised Quality of Life
Oral cancers, a type of Head and Neck cancer, include the lip, tongue, gums, cheeks, the floor (bottom)…
Engaging the Immune System to Treat Gastrointestinal Cancers
June 14, 2021 AFCR News, Innovative Therapies and Treatments, Translational Research
THE CHALLENGE
——High Incidence and Mortality, Few Viable and Dedicated Drugs
Gastrointestinal (GI) cancers including colorectal, stomach, liver, esophageal, and pancreas have high incidence and mortality. Globally, they have the 2nd, 3rd, 4th, 6th, and 7th largest death tolls, respectively, among all cancers.
In 2020,…
Convergence of Western Science and Traditional Chinese Medicine — Botanical Cancer Drug Platform
April 13, 2021 AFCR News, Clinical Research, Innovative Therapies and Treatments
THE CHALLENGE
—Unmet Medical Need for Holistic Cancer Treatment
Cancer is a heterogeneous disease. Heterogeneity in cancer is not limited to differences between different patients, but also occurs within a single patient. This intrapatient or intratumoral heterogeneity can present great challenges for cancer treatment.
This…
Innovation: Therapeutics – anticancer system capable of loco-regional delivery of drug product
Targeted Cancer(s): Solid Tumors, Mucosal Cancers. Initial indication: Oral Cancer
Scientific Leadership/Leadership: Manijeh Goldberg, PhD., President & CEO; James Mackay, PhD., Board Member and Chief Advisor; Nishant Agrawal, MD., Chief Medical Advisor
Stage…
Multi-functional antibodies to target cancer on multiple fronts
March 1, 2020 Innovative Therapies and Treatments, Translational Research
Advanced cancers typically suppress the immune response by multiple mechanisms. By carefully engineering multi-functional antibody therapies, there is the potential for more effective treatment.
A global clinical trial to allow more patients to quickly share benefits of more effective treatments
New Models of Early Cancer Development
August 24, 2018 Basic Research, Early Detection and Prevention, Innovative Therapies and Treatments
Developing appropriate models for diseases such as cancer and Alzheimer’s disease is critical for dissecting their disease…
Ending Drug Resistance to Major Cancer Pathway
August 24, 2018 Basic Research, Innovative Therapies and Treatments
The pathway, Ras/Raf/MEK/ERK, is a cascade of proteins that turn on gene regulators, playing a central role…
Understanding the risk of breast cancer in the Chinese population is very important due to the exponential increase in incidence…
Cell Polarity Proteins in Epithelial Cancers
August 24, 2018 Basic Research, Innovative Therapies and Treatments
More than 80% of tumors originate in epithelial cells, the most common type of cells in the human body. They are found in a wide array of organs, forming the linings and surfaces…
An Innovative Treatment Initiative for Liver Cancer
August 20, 2018 Basic Research, Innovative Therapies and Treatments
Hepatocellular carcinoma (HCC), the most typical form of liver cancer, is the second leading cause of cancer-related fatalities in Asia…
Improving the Treatment of Ovarian Cancer with Powerful microRNAs that Overcome the Resistance of Chemotherapy
April 8, 2018 Basic Research, Innovative Therapies and Treatments
Improving the Treatment of Ovarian Cancer with Powerful microRNAs that Overcome the Resistance of Chemotherapy
Personalized Medicine For Non-Small Cell Lung Cancer Patients
April 8, 2018 Basic Research, Innovative Therapies and Treatments
In China, there are nearly 4.5 million cancer patients and lung cancer is the most common type